What is the function of nucleoporin FG? The function of nucleoporin FG is to clo
ID: 52867 • Letter: W
Question
What is the function of nucleoporin FG?
The function of nucleoporin FG is to clog the central pore region of a nuclear pore complex to preclude the flow of material from nucleus to cytoplasm.
The function of nucleoporin FG is to open the central pore region of a nuclear pore complex to promote the flow of material from nucleus to cytoplasm.
The function of nucleoporin FG is to keep the nucleolus free from mRNA
The function of nucleoporin FG is to promote entry of mRNA into the nucleoplasmic reticulum
The function of nucleoporin FG is to clog the central pore region of a nuclear pore complex to preclude the flow of material from nucleus to cytoplasm.
The function of nucleoporin FG is to open the central pore region of a nuclear pore complex to promote the flow of material from nucleus to cytoplasm.
The function of nucleoporin FG is to keep the nucleolus free from mRNA
The function of nucleoporin FG is to promote entry of mRNA into the nucleoplasmic reticulum
Explanation / Answer
The family of proteins that act as building blocks of nuclear pore complex are called nucleoporins. The transport of macromolecules between cell nucleus and cytoplasm in eukaryotes is mediated by nucleoporins. The functioning of nucleoporins requires transport molecules such as karyopherins (Kaps). The nucleoporins that contain FG peptide repeats will interact with karyopherins. The FG peptide repeats contain repeating sequence of phenyl alanine (F) and glycine (G).
The nucleoporins play an important role in transport of large hydrophilic molecules above 40 kDa, while simple molecules pass through nuclear pores by passive diffusion. It also plays a role in transport of mRNA from nucleus to cytoplasm after transcription.
Thus, the correct option among the following is the function of nucleoporin FG is to open the central pore region of a nuclear pore complex to promote the flow of material from nucleus to cytoplasm.
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