A critical reaction in the production of energy to do work or drive chemical rea
ID: 528928 • Letter: A
Question
A critical reaction in the production of energy to do work or drive chemical reactions in biological systems is the hydrolysis of adenosine triphosphate, ATP, to adenosine diphosphate, ADP, as described by ATP (aq) + H_2O(l) rightarrow ADP(aq) + HPO^2-_4(aq) for which delta G degree_rxn = -30.5 kJ/mol at 37.0 degree C and pH 7.0. Calculate the value of delta G_ rxn in a biological cell in which [ATP] = 5.0 mM. [ADP] = 0.90 mM, and [HPO^2-_4] = 5.0 mM. Delta G_rxn = the hydrolysis of ATP spontaneous under these conditions?Explanation / Answer
Delta G = -RT ln K
Delta G = - 8.314 x 310 ln [ 5.0 x 10-3] [ 0.90 x 10-3] / [5.0 x 10-3]
Delta G = 18075.18 J/mol or 18.075 x 103 KJ/mol
NO
Hydrolysis of ATP is not spontaneous as gibbs free energy change is positive
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