In mice, the wild-type coat color agouti results from the presence of the domina
ID: 52961 • Letter: I
Question
In mice, the wild-type coat color agouti results from the presence of the dominant A allele; aa homozygote animals have a black coat. At least one wild-type allele at another gene, C, is needed for the formation of any pigment; cc animals are albino. The A and C genes are unlinked. You cross a true breeding agouti mouse homozygous for A and C wild-type alleles and albino mice, homozygous for mutant a and c alleles. What are the genotypes of the gametes produced by the F1 offspring?
a. AC and ac
b. AC, Ac, aC, and ac
c. Aa, Cc
d. Ac and aC
Explanation / Answer
So the possible phenotype are agouti, black and albino & their corresponding genotypes are;
A/- C/- : agouti
a/a C/- : black
-/- c/c : albino ( a C allele is required for the formation of any pigment)
A true breeding agouti mouse homozygous for A and C wild-type alleles - AACC
Albino mice homozygous for mutant a and c alleles - aacc
Parents:....AACC........................................X...................................aacc
Gametes: ...AC................................................................ac
F1:...........................................AaCcc
hence, genotype of gametes of F1 progeny will be: AC,Ac,aC,ac
Therefore, the answer is - option (b)
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