A middle-aged man had rough, brown, scaly skin. The man did not realize his cond

Question

A middle-aged man had rough, brown, scaly skin. The man did not realize his condition was inherited until his daughter (who had normal skin) had two sons. One son had skin that resembled his grandfather's. This rare inherited disorder is known as icthyosis and is due to the absence of a single enzyme. The mode of transmission is appears to be:

autosomal recessive

autosomal dominant

X-linked dominant

X-linked recessive

Y-linked

A middle-aged man had rough, brown, scaly skin. The man did not realize his condition was inherited until his daughter (who had normal skin) had two sons. One son had skin that resembled his grandfather's. This rare inherited disorder is known as icthyosis and is due to the absence of a single enzyme. The mode of transmission is appears to be:

autosomal recessive

autosomal dominant

X-linked dominant

X-linked recessive

Y-linked

Explanation / Answer

X-linked recessive - Since the mother of two children appeared as normal bearing two copies of X chromosome, where as her sons having only one copy of X chromosome had the phenotype.

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