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Kinases and phosphatases turn proteins on and off through the following mechanis

ID: 55541 • Letter: K

Question

Kinases and phosphatases turn proteins on and off through the following mechanism:

adding or hydrolyzing GTP, resulting in changes in protein conformation or interaction with other proteins

Adding or removing ubiquitin, resulting in changes in protein conformation or interaction with other proteins

making or breaking disulfide bonds, resulting in changes in protein conformation or interaction with other proteins

adding and removing phosphate groups, resulting in changes in protein conformation or interaction with other protein

A.

adding or hydrolyzing GTP, resulting in changes in protein conformation or interaction with other proteins

B.

Adding or removing ubiquitin, resulting in changes in protein conformation or interaction with other proteins

C.

making or breaking disulfide bonds, resulting in changes in protein conformation or interaction with other proteins

D.

adding and removing phosphate groups, resulting in changes in protein conformation or interaction with other protein

Explanation / Answer

Protein kinases and protein phosphates counteract each other in turning on or off proteins. The protein kinases add a phosphate group to bring about necessary confirmational changes in a target protein. The protein phosphatases remove a phosphate group to cause confirmational changes in target protein. Hence, option D is correct.