3. The Lethal dose (LDS0) is the amount of an ingested substance that will kil 5

Question

3. The Lethal dose (LDS0) is the amount of an ingested substance that will kil 50 percent of the test sample. It is usually expressed in mg of substance per kg of body weight (mg/kg). FD&C; Blue Dye #1 has an LD50 of 300 mg/kg. Determine the mass of blue dye that would be required to reach the LD50 for a 150lb person. Dyes have very high molar absorptivity. Why is this an advantage for their use in food products? T as h 4. Compond has mol sorp tu ofduewhch win efffcantiy absorb Suff Ce lour for 2 Whyis it done?

Explanation / Answer

for a m = 150 lb = 150*454 g = 68038.9 g = 68.0399 kg

then..

C = 300 mg/kg

total mass reuqired for LD = 68.0399 *300 = 20411.97 mg of Blue dye required

Total mass ( in grams) = 20411.97/!000 = 20.41 g of Blue dye

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