atch each of the reactions in the beta-oxidation of palmitic acid, a C16 fatty a

Question

atch each of the reactions in the beta-oxidation of palmitic acid, a C16 fatty acid to its stage in the process: activation, first oxidation, hydration, second oxidation, or cleavage Palmitoyl-CoA and FAD form alpha,beta unsaturated palmitoyl CoA and FADH2 Choose ] hydration second oxidation cleavage first oxidation activation Beta-keto palimitoyl CoA forms mystistoyl CoA and acetyl-CoA. Palimitic acid, CoA, and ATP form palmitoyl CoA. IChoose l alpha,beta-Unsaturated palmitoyl-CoA and H Choose l form beta-hydroxy palmitoyl-CoA. beta-hydroxy palmitoyl-[Choose] CoA and NAD+ form beta-keto palmitoyl-CoA and NADH+H

Explanation / Answer

beta oxidation of fatty acids generally involve 5 steps in the order

1) activation

2) first oxidation

3) hydration

4)second oxidation

5) cleavage

ACTIVATION is nothing but formation of palmitoyl CoA when CoA reacts with ATP in presence of coenzyme A and MG2+

FIRST OXIDATION involves reaction of palmitoyl CoA with FAD forms FADH2 along with alpha-beta unsaturated palmitoyl CoA

HYDRATION as name indicates it is reaction with water

that is the product in first activation which is unsaturated alpha-beta palmitoyl CoA reacts with water(H2O) forms beta-hydroxy palmitoyl CoA

SECOND OXIDATION now the product of hydration which is beta-hydroxy palmitoyl CoA dehydrogenase catalyses the second oxidation and generates NADH

the product formed is beta-ketoacyl CoA

CLEAVAGE this is final step in the process that is liberation of 2 carbon fragment ,acetyl CoA from acyl CoA

that is beta-ketoacyl CoA forms acyl CoA which again reenters the beta-oxidaation process

this process continues til the fatty acid completely oxidizes

so based on ths theory matching involves

giving numbers in increasing order to the reactions given in the question

matching

1----->FIRST OXIDATION

2------>CLEAVAGE

3------->ACTIVATION

4------->HYDRATION

5------->SECOND ACTIVATION

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