Which of the following species is the best mucleophile in methanol? CH S CHO NH,

Question

Which of the following species is the best mucleophile in methanol? CH S CHO NH, 7. In the Sollowing reaction, which base most favors the anti-Zaitsev product? C. . Which of the following coempounds undergoes an E2 reaction most readily? E. 9. Which of the following bases most favoes elimination over substitution? 10. What are the substitution products of the following reaction? CH3CH2Br + "OH ? B) HOCH2CH2Br C) CH3CH20OH+Br D) CH2-CH2z+ Br+ H20 E) CH2-CHBr + H20 11. Which of the following alkyl halides reacts the fastest in an Sn2 reaction? A) 2-chloro-2-methylpropane B) 2-chlorobutane C) 1-chlorobutane D) chloromethane 12. How does doubling the concentration of both the allkyl halide and the nucleophile affect the

Explanation / Answer

Ans 6 : F-

A nucelophile is the species that donates its pair of electrons to form the covalent bond. Methanol is a polar protic solvent , where the nucleophilicity depends on the ability to form the hydrogen bonds. The higher tendency to form the hydrogen bonds leads to weaker nucleophilic character.

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