19. Why is an anaerobic fate A) of pyruvate necessary in skeletal muscle? It is

Question

19. Why is an anaerobic fate A) of pyruvate necessary in skeletal muscle? It is required to maintain the reducing environment of the cytosol B) It allows for the re-oxidation of NADH to NAD', as NAD" is in limited supply during anaerobic conditions. t decreases the pl of the skeletal muscle cell,thereby increasing release of oxygen D) E) from myoglobin. All of the answers are correct. None of the answers is correct. 20. Which compound is NOT required for the oxidative decarboxylation of pyruvate to form acetyl-CoA? A) ATP B) CoA-SH C) FAD D) lipoic acid E) NAD 21. Which statement about the oxidative decarboxylation of pyruvate in aerobic conditions in animal cells is CORRECT? A) One of the products of the reactions of the pyruvate dehydrogenase complex is a thioester of acetate. B) The methyl (-CHs) group is eliminated as CO2. C) The process occurs in the cytosolic compartment of the cell. D) The pyruvate dehydrogenase complex uses all of the following as cofactors: NAD, lipoic acid, pyridoxal phosphate (PLP), and FAD. The reaction is so important to energy production that pyruvate dehydrogenase operates at full speed under all conditions. E) 22. Which compound is NOT an intermediate of the citric acid cycle? A) acetyl-CoA B) citrate C) oxaloacetate D) succinyl-CoA E) -ketoglutarate 23. In mammals, what process does NOT occur during the citric acid cycle? A) formation of a-ketoglutarate B) generation of NADH and FADH2 C) metabolism of acetate to carbon dioxide and water D) net synthesis of oxaloacetate from acetyl-CoA E) oxidation of acetyl-CoA

Explanation / Answer

Ans 19 : B) It allows for the re-oxidation of NADH to NAD+ , as NAD+ is in limited supply during anaerobic conditions.

The anaerobic conditions lead to the frementation process , where the pyruvate is converted into lactic acid. The lactic acid produced decreases the pH and causes acidosis. The NADH is converted into NAD+ , so that the glycolysis process can continue uninterruptedly.

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