The following is true regarding the LDL receptor: The LDL receptor binds to LDLs
ID: 56495 • Letter: T
Question
The following is true regarding the LDL receptor:
The LDL receptor binds to LDLs and HDLs
The LDL is located inside of the nucleus
The LDL receptor does not undergo a conformational change upon binding LDL
The LDL receptor undergoes endocytosis within Clathrin coated vesicles upon binding LDL
The LDL receptor binds to LDLs and HDLs
The LDL is located inside of the nucleus
The LDL receptor does not undergo a conformational change upon binding LDL
The LDL receptor undergoes endocytosis within Clathrin coated vesicles upon binding LDL
Explanation / Answer
The LDL receptor undergoes endocytosis within Clathrin coated vesicles upon binding LDL. LDL receptor complexes occurring in clathrin-coated pits on their surface, when bound to LDL-cholesterol through adaptin protein, are internalized to form clathrin-coated vesicles inside the cell. This allows LDL-cholesterol to be bound and internalized through a process known as endocytosis. Option 4 is correct.
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