Etiology of most autoimmune diseases is idiopathic. However, many diseases have

Question

Etiology of most autoimmune diseases is idiopathic. However, many diseases have identified “contributing factors” that provide some insight about etiology. Which of the following do NOT increase your risk for Multiple sclerosis? Select all that apply:

A. Advanced age (over 60)

B. Estrogen exposure

C. High levels of vit D

D. Variant forms of genes that code for MHCs on chromosome 6

E. Being Native American

F. Testosterone exposure

A. Advanced age (over 60)

B. Estrogen exposure

C. High levels of vit D

D. Variant forms of genes that code for MHCs on chromosome 6

E. Being Native American

F. Testosterone exposure

Explanation / Answer

Advanced age (over 60)

High levels of vit D

Variant forms of genes that code for MHCs on chromosome 6.

Being Native American. All these do not increase the risk of multiple sclerosis. Options A, C, D and E are correct.

People aged between 15 - 60, people of European descent; females and males, smoking, certain viral infections are contributing factors to multiple sclerosis.

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