Your future self identifies a particular mutation in human cells that results in

Question

Your future self identifies a particular mutation in human cells that results in abnormal cell growth. You name this mutation swiftT. You then identify that this mutation in a gene that codes for a FGFR protein and you find that people who have the swiftT mutation are 275% more likely to develop some form of cancer those those humans with the wt FGFR. You sell your research to pharmaceutical company and the company first tries to target and alter all kinase activity in cells that carry the swiftT mutation. However, the treatment never reaches clinical trails due to severe adverse effects in various tissue culture cell types. Why do you think this treatment plan failed?

Explanation / Answer

The treatment never reaches clinical trails due to severe adverse effects in various tissue culture cell types because the mutation swiftT causes a defect in cell signaling . It leads to disruption in cell growth and development. Thus adverse effects is cell types of the culture which may ultimately lead to Apoptosis of normal cells. Hence the treatment plan failed.

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