Which among the listed phenomena is not a characteristic of the symmetry alloste

Question

Which among the listed phenomena is not a characteristic of the symmetry allosteric MWC model:

a.symmetrical relationship between promoters in an oligomer

b.each promoter can exist in at least two conformational states in an equilbrium

c.ligand binds to a promoter in each configuration, but with different affinity

d.conformational change takes place simultaneously for all promoters in an oligomer

e.upon binding of a ligand there is a sequential change in the conformation of the promoters in the oligomer

Explanation / Answer

The incorrect option is b because it is from another model in which the enzyme exists in two states whithout interaction among them. This is the rigid adjusted model. In this model, the affinity among sustrates and enzyme remains constant.

In the MWC model the affinity among sustrates and enzyme increases with the previous sustrate's bonding.

The incorrect option is b.

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