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Given that successful management of Type I diabetes requires individuals to rema

ID: 58400 • Letter: G

Question

Given that successful management of Type I diabetes requires individuals to remain vigilant about their food intake, relative levels of activity, blood glucose levels, and insulin dosage, it is easy to understand why numerous investigators currently are seeking solutions that involve permanent replacement of insulin-producing cells in the patient’s pancreas. In addition to the ability to synthesize and release insulin, what property would these “synthetic beta cells” need to fully restore the functionality of the pancreas with regard to the dynamics of insulin release?

Explanation / Answer

The synthetic beta cells seems to be the promising choice for type - I diabetes mellitus, in which synthesis and release of insulin is impaired. Apart from the ability of synthesising and releasing the insulin, the synthetic beta cells must be sentive enough to regulate the release of insulin according to the need, means not causing hypo or hyper secretion of insulin.

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