1. The equation is the definition of population average fitness 2 the symbol u r
ID: 58962 • Letter: 1
Question
1. The equation is the definition of population average fitness
2 the symbol u refers to the mutation rate toward seltoviekt neutral mutations
3 the symbol u refers to the mutation rate toward harmful mutations
4 w1 refers to the genetic fitness of the Normal allele
5. W1 refers to the genetic fitness of the harmful allele 6 this equation will be true no matter the allele frequencies 7 the equation is only true if the population is at equilibrium between selection and mutation
8. This equation derives from a model where mutations are assumed to occur only from the normal allele to the harmful one not the reverse. 9. Equation applies only to recessive harmful mutations 10 the equation shown applies to only the harmful mutations which can be dominant or partially dominant
Explanation / Answer
3) The symbol u refers to mutation rate towards harmful mutation is correct.
4) w1 refers to the genetic fitness of the Normal allele is correct.
7) If an infinitely large population is in a mutation–selection balance, then the mutation load L is independent of the fitness effects of the mutations. That is, if µ denotes the total mutation rate from the wildtype (the allele with the highest fitness, normalized to 1) to all other possible alleles, then the mean fitness of the population W is
mean W = 1 L = 1 µ ...independent of the fitness values of the mutants (except for completely recessive alleles).
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