Which of the following statements accurately describe receptor tyrosine kinases

Question

Which of the following statements accurately describe receptor tyrosine kinases (RTKs)? There is more than one correct answer. Select all the true statements( must pick the correct 4 ones)*

A. The intracellular domain has phosphatase domains.

B. RTKs are usually (but not always) monomeric in the absence of ligand.

C. A ligand binds to the extracellular domain.

D. Ligand binding is required for autophosphorylation (cross-phosphorylation).

E. The subunit contains seven helices that span the membrane.

F. The structure includes a transmembrane helix.

WRONG anser comboination i have tried ACDF, ABCF, plese help!!!

Explanation / Answer

The correct answers are:

B. RTKs are usually (but not always) monomeric in the absence of ligand.

C. A ligand binds to the extracellular domain.

D. Ligand binding is required for autophosphorylation (cross-phosphorylation).

F. The structure includes a transmembrane helix.

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