The question is from my oncology(cancer biology) class.. I don\'t remember the e

Question

The question is from my oncology(cancer biology) class.. I don't remember the exact question, but I think the question was..

"Explain in detail about 3 pathways of ras" (PIP3, Raf, Inositol lipids & Akt???)

My professor wants a very long, detailed explaination for each assignment... and I seriously have no idea, and didn't even start studying the cell signaling part.

I will really really appreciate it if you could explain in detail, including what is ras.. and etc, etc...

p.s. The textbook for this course is cancer biology written by Robert. A. Weinburg

Explanation / Answer

RAS protein control signalling pathway for regulator of normal cell growth and malignant transformation

RAS protein are essential for controlling cellular proliferation, differentation ..mutation leads to tumor .there are different types of ras gene like H.ras ,Nras,and K.ras reported in human

Hras mutation are common in bladder, kidney

N ras mutation common in melanoma

K ras mutation occur in pancreas

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