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George is a 76-year-old male who presents to the clinic with complaints of frequ

ID: 59985 • Letter: G

Question

George is a 76-year-old male who presents to the clinic with complaints of frequent nosebleeds (four in the past week) and easy bruising. The patient also complains of a runny nose and cough. He has a history of chronic atrial fibrillation and takes warfarin. About 3 weeks ago, the patient started taking Tagamet over-the-counter (OTC) for heartburn.

What problems with this patient can you identify? What contributes to this patient’s increased blood pressure? What are the mechanisms and ALL interactions associated with this drug regimen?

Medications

Digoxin 0.25 mg QD

Cimetidine OTC BID

Pseudoephedrine SR 120 BID

Warfarin 7 mg QD

Allergies: NKDA

Physical Examination

VS: BP: 180/95, HR 75, irregularly irregular, RR 17, Wt. 95 kg

HEENT: WNL

ABD: + Bowel Sounds

EXT: Bruising on arms and legs

NEURO: Alert & Oriented x 3

GEN: Well developed, well-nourished male.

ECG: atrial fibrillation.

Laboratory

Na 143

K 4.5

Cl 99

CO2 25

BUN 18

SCr 0.9

INR 4.8

Hct 42

Hbg 15

Digoxin 1.6ng/ml

Medications

Digoxin 0.25 mg QD

Cimetidine OTC BID

Pseudoephedrine SR 120 BID

Warfarin 7 mg QD

Allergies: NKDA

Physical Examination

VS: BP: 180/95, HR 75, irregularly irregular, RR 17, Wt. 95 kg

HEENT: WNL

ABD: + Bowel Sounds

EXT: Bruising on arms and legs

NEURO: Alert & Oriented x 3

GEN: Well developed, well-nourished male.

ECG: atrial fibrillation.

Laboratory

Na 143

K 4.5

Cl 99

CO2 25

BUN 18

SCr 0.9

INR 4.8

Hct 42

Hbg 15

Digoxin 1.6ng/ml

Explanation / Answer

The patient is suffering with Chronic atrial fibrillation causing abnormal heart beat or cardiac arrythmia as a result of blood pressure or other heart complications particularly attacking age old persons. It leads to blood clots, heart stroke, heart palpitations.

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