6) Mutations in the genes needed to repair damaged chromosome DNA in cells can p

Question

6) Mutations in the genes needed to repair damaged chromosome DNA in cells can promote the transition of these normal cells to become cancer cells by

Select one or more:

increasing the rate at which mutations are produced in genes that are employed in the cell cycle.

decreasing the number of tumor suppressor genes in the genome.

failing to repair damage in the chromosome DNA.

allowing mutations to accumulate in the chromosomal DNA of the cells.

causing the cells to lose control of the cell cycle and grow unrestrained.

7) A human spectral karyotype is a beautiful display of human chromosomes that are 'painted' with DNA-specific fluorescent probes that identify each chromosome by color. Which of the following mutations would never be visible on a human spectral karyotype?

Select one or more:

A chromosome translocation

A DNA point mutation (single base pair change) in the coding region of a gene

A chromosome segment deletion

The gain of an entire chromosome

A DNA point mutation (single base pair change) in the regulatory region of a gene

8)Damage to the cell's genome DNA can be very dangerous to cells, but cells have evolved special enzymes and biochemical mechanisms that repair damaged DNA. As people get older the DNA repair mechanisms in the cells

Select one:

are quickly replaced by new repair components that can maintain the fidelity of the DNA.

begin to fail rapidly and most of the new mutations delete entire coding regions of genes.

improve their ability to protect the DNA from damage.

begin to fail so that changes in the DNA genome sequence accumulate over time.

are replaced with alternate pathways that are less efficient at repairing DNA damage.

9)Amniocentesis and chorionic villus sampling (CVS) are both prenatal tests used to analyze the genetic status of a fetus before birth. Which of the following characteristics do the amniocentesis and CVS tests have in common?

Both tests are

Select one:

used to harvest stem cells that can be used to regenerate tissues for the unborn child.

performed on fetal cells.

designed to analyze the number and structures of the chromosomes.

performed to confirm the number of sex chromosomes in maternal cells.

performed on placental cells.

10)You are studying a newly identified, relatively rare disease that seems to run in families. It is equally likely in males and females. When one parent has the disease but the other does not, it appears that about half of the children of these parents get the disease. You conclude that the disease is

Select one:

Y-linked dominant.

autosomal codominant.

autosomal dominant.

autosomal recessive.

X-linked recessive.

Explanation / Answer

6. causing the cells to lose control of the cell cycle and grow unrestrained.

7. A DNA point mutation (single base pair change) in the coding region of a gene, A DNA point mutation (single base pair change) in the regulatory region of a gene

8. begin to fail so that changes in the DNA genome sequence accumulate over time

9. designed to analyze the number and structures of the chromosomes

10. Autosomal dominant

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