An shRNA is generated from a plasmid, how and what are its effects? The shRNA bi

Question

An shRNA is generated from a plasmid, how and what are its effects?

The shRNA binds to DNA and inhibits transcription

A single strand of the shRNA binds to the complementary mRNA coding sequence

and suppresses target expression

A single strand of the shRNA binds to the complementary mRNA coding sequence and

enhances target expression

The shRNA binds to RNA Pol II causing retroinversion and suppression of the targets

transcription

The shRNA binds to DNA and inhibits transcription

A single strand of the shRNA binds to the complementary mRNA coding sequence

and suppresses target expression

A single strand of the shRNA binds to the complementary mRNA coding sequence and

enhances target expression

The shRNA binds to RNA Pol II causing retroinversion and suppression of the targets

transcription

Explanation / Answer

A single strand of the shRNA binds to the complementary mRNA coding sequence and suppresses target expression

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