PLEASE SHOW ALL WORK 1. A nerve cell has an axon that extends 3 cm with an inter

Question

PLEASE SHOW ALL WORK

1. A nerve cell has an axon that extends 3 cm with an inter-node spacing of 2 mm. Calculate the membrane potential at a node just prior to the generation of an action potential given the following information:

Membrane length constant = 1 mm
Threshold = -35 mV
Resting membrane potential (RMP) = -60 mV
Action potential overshoot = +20 mV.

What is the membrane potential at the next node, and is depolarization sufficient to generate another action potential?
% Response = 100(1 - e-l/)

-49 mV, and an AP will NOT occur at node 2
-30 mV, and an AP WILL occur at node 2
-69 mV, and an AP WILL occur at node 2
-25 mV, and an AP will NOT occur at node 2

Explanation / Answer

Based on the given data,

The formula for calculation is as follows:

Therefore,

Thus, the membrane potential at a node just prior to the generation of an action potential is 0.2 mV.

(b)

% Response = 100(1 - e-l/)

=100 (1-2.7-(0.2/1))

= -190 mV

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