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Which of the following would cause GPK activity to be 50% upon the addition and

ID: 62229 • Letter: W

Question

Which of the following would cause GPK activity to be 50% upon the addition and subsequent removal of epinephrine to a mutant liver cell?

Ca2+ channels on the ER were unable to bind IP3

A.

Ca2+ channels on the ER were unable to bind IP3

B. Certain S or T on the alpha or beta subunits of GPK were changed to A C. Certain S or T on the gamma subunit of GPK were changed to A D. Certain S or Ts on the alpha or beta subunits of GPK were changed to E E. Certain S or Ts on the gamma subunit of GPK were changed to E

Explanation / Answer

A. Ca2+ channels on the ER were unable to bind IP3

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