26. Mutations that disrupt splicing of eukaryote RNAs would most likely be locat

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26. Mutations that disrupt splicing of eukaryote RNAs would most likely be located in the A. 5-untranslated sequences B. exon sequences C. conserved intron sequences D. non-conserved intron sequences. E. 3'-untranslated sequences. 27. Suppose a gene encodes an RNA with 5 -Exon1.-Intron1.-.Exon2-3 A phosphodiester bond eventually from links the two exons. The electrons for connecting Exon 1 to Exon 2 comes A. 3'-OH of Exon2. B. 2-OH of Exon2. C. 3-OH of Exon1. D. 2-OH of Exon1 E. 3'-OH of the U5 snRNA. 28. In order for oxidation of guanine to 8-oxoguanine to produce a stable, long-lasting mutation, the A. oxidized DNA must be transcribed into RNA B. RNA transcript from the oxidized DNA must be translated by ribosomes. C. mutant polypeptide must disrupt cell function. D. cell with the oxidized DNA must undergo two mitotic divisions. E. All of the above. 29. DNA glycosylases A. cleave lactose into monosaccharaides for glycolysis B. remove a damaged base from DNA C. insert the correct base after the damaged base has been removed. D. synthesize the final phosphodiester linkage after the correct base has been incorporated E. All of the above. 30. A loss-of-function mutation in a negative regulator of an inducible process A. causes the process to be constitutive. B causes the process to be non-inducible. C. has no effect on the process. D. cannot be predicted 31. A loss-of-function mutation in a positive regulator of an inducible process A. causes the process to be constitutive B causes the process to be non-inducible. C. has no effect on the process. D. cannot be predicted 32. Example(s) of a positive regulator is/are A. the lac repressor (I gene). B the CAP protein. C the GAL4 protein. D- the GAL80 protein. E. both B and C. 33. A benefit of prokaryotic operons is that it A. coordinately activates or represses genes that encode functionally related enzymes B. provides maximum flexibility in choosing which genes are activated or repressed. C. prevents transposons from inserting and disrupting gene expression D. maximizes the number of translated proteins by creating additional alternative splicing sites E. All of the above.

Explanation / Answer

Ans-26 -(C) , Ans-29 -(B), Ans-30 (A) , Ans-31 ( B) , Ans-32 (B)

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