Using genetic engineering techniques, you have created a set of proteins that co

Question

Using genetic engineering techniques, you have created a set of proteins that contain two (and only two) conflicting signal sequences that specify different compartments. Predict which signal would win out for the following combinations, meaning if the protein has two conflicting sorting signals, where would the protein end up? Explain your reasoning.

A. Signal sequence for import into the chloroplast and signal sequence for import into the ER

B. Signal sequence for export from the nucleus and signal sequence for import into the mitochondria

C. Signal sequence for import into nucleus and signal sequence for retention in the ER

Explanation / Answer

Option C ; signal sequence for import from the nucleus and signal sequence retension into ER .

each protein is destined by its amino acid sequence to go to certain places and to do certain things ,different proteins have different signalling sequences ,change in the aminoacid sequence results in the improper transport and processing the proteins so that the abnormal proteins do not enter normal position for protein . They are 3 types of the transport system Nuclear pores , Translocation across the memberane , vesicle transport.

Er retension signal most of the newly synthsiesed secretory proteins are transported from the ER to the golgi appratus .If these proteins are have a perticular 4 aminoacid retension sequence for the Er lumen ,KDEL , on their C terminus .they are retained in the Er lumen or routed back to the Er lumen via interaction with KDEL receptor in the golgi apparatus ,the retension sequence is similar to the protein will be transmembranal.

Related Questions

Navigate

• Browse (All)
• Browse U
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.