Avidin is a protein that binds extremely tightly to biotin, so avidin is a poten

Question

Avidin is a protein that binds extremely tightly to biotin, so avidin is a potent inhibitor of biotin-requiring enzyme reactions.

Part A

Consider glucose biosynthesis from each of the following substrates and predict which of these pathways would be inhibited by avidin.

Check all that apply.

Avidin is a protein that binds extremely tightly to biotin, so avidin is a potent inhibitor of biotin-requiring enzyme reactions.

Part A

Consider glucose biosynthesis from each of the following substrates and predict which of these pathways would be inhibited by avidin.

Check all that apply.

Check all that apply. phosphoenolpyruvate lactate malate fructose-6-phosphate oxaloacetate

Explanation / Answer

Biotin is the cofactor that is involved in the conversion of pyruvate to oxaloacetate in the presence of an enzyme called pyruvate carboxylase. The lactate is converted to form pyruvate in the presence of an enzyme called lactate dehydrogenase. The pyruvate, which is formed from lactate is converted to form oxaloacetate in the presence of biotin. Thus, in the given case, avidin can inhibit biosynthesis of glucose from lactate.

Hence, the correct option among the following is lactate.

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