1- Please perform a broad literature search about all the ways nanotechnologies
ID: 62924 • Letter: 1
Question
1- Please perform a broad literature search about all the ways nanotechnologies have been applied to type1 diabetes disease . Up until now, my course has focused mostly on nanoparticles for drug delivery, but there a lot of other ways nanomedicine can also make a difference. You are encouraged to think about nanotechnology for screening, diagnosis, prevention, and/or treatment monitoring. And don’t limit yourself only to nanotechnologies that are put in the body, there are also a lot ex vivo tools that can be used outside of the body! ,please provide a short summary of each of the ways nanotechnology is being applied to each of these areas.
Explanation / Answer
Diabetes cases have increased at a rapid rate globally, and researchers throughtout the world are exploring variuos technologies to detect/diagnose and treat Diabetes effectively.Nanotechnology offers a wide range of sensing technologies that provide almost accurate and timely medical information for diagnosing diseases, and miniature devices can also can administer treatment automatically if there is need.Recently, nanotechnology offers new implantable or wearable sensing technologies that provide continuous and extremely accurate medical information. Nanomedicine and nanotherapeutics is rapidly evolving in the past five years and these technologies can be applied in various areas of type 1 Diabetes disease (T1D).
1. Detection/diagnosis of Diabetes.
2. Treatment of Diabetes
3. Treatment and monitoring devices:
4. Prophylaxis of Diabetes
The following scientific publications could throw more light on this topic.
1. Nanoparticle based insulin delivery system: the next generation efficient therapy for Type 1 diabetes.Chiranjib Chakraborty et.al 2015, Journal of Nanobiotechnology.
2. Nanotechnology and the future of diabetes management.Danny Meetoo et.al,2009.Journal of Diabetes Nursing.
3. A brief glimpse over the horizon for type 1 diabetes nanotherapeutics.Yesica Garciafigueroa et.al,2015.Clinical Immunology.
4. Managing diabetes with nanomedicine: challenges and opportunities.Robert Langer et.al 2014.Nature Reviews Drug Discovery
5.What potential is there for liposomal-based nanotherapy for the treatment of Type 1 diabetes?.Marta Vives-Pi et.al,2015.Nanomedicine Future Medicine.
6.A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice.Keselowsky et.al,2015. Nature Scientific Reports.
7.A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes.Feldman et.al,2014.Nature Medicine.
8.The role of nanotechnology in diabetes treatment: current and future perspectives. Shaker A. Mousa et.al,2011. International Journal of Nanotechnology.
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