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The genes for both hemophilia A and red-green colorblindness are located on the

ID: 63593 • Letter: T

Question

The genes for both hemophilia A and red-green colorblindness are located on the X chromosome, with about 10cM between them. Linkage of a disease gene, such as hemophilia, to a relatively harmless one, like colorblindness, can often be used to predict the genotypes (i.e. risk of inheritance of the disease gene) of offspring. The pedigree below illustrates such an example. [Vertical lines indicate individuals who are colorblind; horizontal lines indicate individuals who are hemophiliacs.]

For both parts of this problem, assume there is no crossing over in female III-4, but do not make that assumption for female II-1.

Part A

If female III-4 marries a normal male, what proportion of her sons are expected to be completely normal (normal color vision, no hemophilia)?

Enter your answer as a whole number. Do NOT add the % symbol -- it's included with the answer box.

111

Explanation / Answer

50 is the correct answer

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