1. Match the antibiotic with the correct mechanism of action on the right. *Stre
ID: 636205 • Letter: 1
Question
1. Match the antibiotic with the correct mechanism of action on the right.
*Streptomycin
*Erythromycin
*Chloramphenicol
*Puromycin
*Tetracycline
A) inhibits the binding of aminoacyl-tRNAs to the ribosome
B) interferes with normal pairing between aminoacyl-tRNAs and mRNA codon
C) binds to 23s RNA
D) causes premature chain termination
E) blocks elongation by acting as a competitive inhibitor of the peptidyl transferase complex
2. Which of the following amino acid sequences would NOT be produced by the translation of the repeating mRNA sequence (GCU)n (where n= number of repeating units)?
A) (-C-C-C)n
B) (-S-S-S)n
C) (-A-A-A)n
D) (-L-L-L)n
3. An ________ is a sequence within a mRNA that is bounded by stop and start codons that can be continuously translated. (Fill in the blank)
4. Termination of translation occurs when a stop codon is translocated into the ____ site of the ribosome. (Fill in the blank)
Explanation / Answer
Answer 1 :-
*Streptomycin ---> B) interferes with normal pairing between aminoacyl-tRNAs and mRNA codon
*Erythromycin ----> E) blocks elongation by acting as a competitive inhibitor of the peptidyl transferase complex
*Chloramphenicol ----> C) binds to 23s RNA
*Puromycin ---> D) causes premature chain termination
*Tetracycline ----> A) inhibits the binding of aminoacyl-tRNAs to the ribosome
Answer 2 :- (A) (-C-C-C)n
Answer 3 :- An open reading frame is a sequence within a mRNA that is bounded by stop and start codons that can be continuously translated.
Answer 4 :- Termination of translation occurs when a stop codon is translocated into the A site of the ribosome.
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