my disease is malaria and this is the assingnment !. this my last assignment ple
ID: 63666 • Letter: M
Question
my disease is malaria and this is the assingnment !. this my last assignment please i want more information?. This week, we want you to narrow down on one topic from last week and research it in more detail. The topic you pick this week will be central theme of your term paper! When picking your focused topic, you will want to research what is the strongest clinical need - should you test for the disease in a healthy population, should you confirm a diagnosis in someone already suspected to have the disease, or do you need a robust way to measure whether a treatment is working? Or is there a way to prevent disease progression rather than just treating the symptoms of your disease? Once you have settled on the strongest clinical need, please research your chosen topic in more detail., Like last week, be sure to take good notes, you will be using the materials you find to write your term paperExplanation / Answer
Of course, you need to have the blood samples from non-endemic and endemic healthy individuals, other infectious diseases (like TB, typhoid, leishmaniasis) to negotiate the cross-reactivity with you malaria suspected individuals blood samples. Here, non-endemic is a pure negative control for the disease, endemic is nothing but healthy, which were bitten by the vector (mosquitoes) but not carrying plasmodium pathogen. They used to have antibodies against mosquitoes salivary proteins. Other infectious samples would provide cross-reactivity if they have common proteins in different pathogens causing diseases. Now, your suspected samples will give actual results after subtraction of the endemic sample values (in ELISA diagnosis) from your original suspected sample values. If your suspected samples O.D is close to other diseases there would be some other infections affected that individual since, your loaded antigen in the ELISA plate is specific for the malaria parasite. You can find out the specificity and sensitivity of ELISA to confirm your suspected samples have the disease.
To conclude whether the treatment is working or not? you need to diagnose in a large group of samples in different phases (I, II, III trails). Here, one more to prevent the disease spread is controlling the vector prevalence or their bite during bedtime by using bed nets. Taking the other prophylactic measure and the surveillance of malnutrition and co-infections would give a better opportunity to control the disease rather than using symptomatic treatment. In nanotechnology, there is a method called live imaging that can track the drug distribution, its bioavailability and excretion is attaining more importance in recent days to know the drugs distribution in the animals. If the drug is specific to parasite of malaria that will keenly bind to the parasite, which can also be tracked out trough live imaging for the confirmation of parasite presence (diagnosis) and drug effect on the parasite in the infected cells.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.