Return to Site (3 of 5) Using the data shown in the graph below determine which

Question

Return to Site (3 of 5) Using the data shown in the graph below determine which statement is correct. 100 0 Kd Kd 10 LI (uM) O The protein shown in binding curve B has a greater affinity for it's ligand as compared to the protein shown in binding curve A. OIf the IL] were 1 uM the percent saturation of A would be greater than B. O The percent saturation of A is expected to be greater than B at all [L]. O B has a lower affinity for its ligand, relative to A, and is therefore never expected to reach 100% saturation. 0 If [L] were to double it is expected that Y would also double at all points along the curve.

Explanation / Answer

Ans : B has a lower affinity for its ligand , relative to A and is therefore never expected to reach 100% saturation.

The curve in right i.e. B has lower affinity for its ligand , due to which it dissociates easily , and hence has a lower percent dissociation , whereas the curve on left , i.e. A curve has higher affinity towards its ligand , and hence lesser percent saturation.

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