What are the general names of the areas responsible for GTP hydrolysis by GTPase

Question

What are the general names of the areas responsible for GTP hydrolysis by GTPases and the association with downstream effectors?

Wrong Answer:

GEF binding domains

Answers:

Regulatory and Catalytic holoenzymes

Switch I and Switch II

GEF binding domains

Ras/Raf domains

What are the general names of the areas responsible for GTP hydrolysis by GTPases and the association with downstream effectors?

Wrong Answer:

GEF binding domains

Answers:

Regulatory and Catalytic holoenzymes

Switch I and Switch II

GEF binding domains

Ras/Raf domains

Explanation / Answer

Correct answers

Switch I and Switch II

GEF binding domains

Ras/Raf domains

Wrong answer - Regulatory and Catalytic holoenzymes

An enzyme together with the cofactor(s) required for activity is called a holoenzyme

Cyclic AMP-dependent protein kinase (cAPK) exists as an inactive tetramer (R2C2) that dissociates in the presence of cAMP to release two active catalytic (C) subunits and a dimeric regulatory (R) subunit

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