The primary mechanism of drug resistance due to drug-resistance plasmids is: enz

Question

The primary mechanism of drug resistance due to drug-resistance plasmids is: enzymatic alteration (inactivation) of the drug. increased elimination of the drug through efflux pumps. altered structural target decreased uptake; change in permeability. increased production of a competitive substrate. Answer the following questions (91-100) on the exam sheet. each question is worth 1 point. 91. What is the definition & the difference between a VRSA & MRSA? What specifically is a XRB-TB?. What specifically is a CRE? Normal antimicrobial therapy for active tuberculosis involves: drug for 10 days. two or more drugs for 10 days. one drug for at least 6 months. three or four drugs for al least 6 months. six or more drugs for at least 3 y cars. 94. Answer to above therapy for active TB (pick one from A-E above)Also what are the mainstay drugs you would use for active TB based on your answer: and what drug for prophylaxis for exposure to an active case

Explanation / Answer

90. The primary mechanism of drug resistance due to drug resistant plasmids is increased production of a competetive substrate.

Plasmids are the extra DNA carried by bacteria; they are transferred to other cells during the process of conjugation. The genes carried by plasmids code for proteins that are involved in unusual metabolic functions, and some carry genes that code for proteins that offer resistance to bacteria. The resistant bacteria do not respond to antibiotics.

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