You are mapping several chromosomal deletions in Drosophila. Each deletion is ho

Question

You are mapping several chromosomal deletions in Drosophila. Each deletion is homozygous lethal. For heterozygotes, a deletion combination is lethal if the two deletions overlap each other and therefore delete some of the same material.

You have five deletions (DF1 – DF5) that you need to map to each other to determine if they overlap, and if so, whether they overlap completely or partially.

Part A DF1 DF2 DF3 DF4 DF5 You cross stocks heterozygous for these deletions to each other, and record whether the deletions are lethal or viable as double heterozygotes y heterozygous for deletion DF1 and deletion DF3 FX For example, flies that are simultaneously heterozygous for deletion DF1 and deletion DF3 die (indicated with an X in the chart). In contrast, flies simultaneously heterozygous for deletions DF1 and DF2 survive (indicated with a check mark) DF2 DF3 DF4 DFS Use the data in the chart to identify the location of each deletion on the map below. The top line on the map represents the undeleted chromosome on the five other lines, the extent of each deletion is represented by the brackets. Drag the label for each deletion next to the appropriate chromosome. The location of one deletion (DF1) has been identified for you.

Explanation / Answer

a. DF3

b. DF5

c. DF2

d. DF4

Take into account the X marks which actually mark the deleted sites.

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