What is meant by the term chromatin remodeling? Select the two correct answers.
ID: 66119 • Letter: W
Question
What is meant by the term chromatin remodeling? Select the two correct answers. Chromatin remodeling includes altering chromatin structure by altering the positioning of nucleosomes with respect to specific DNA sequences. Chromatin remodeling includes altering chromatin structure by IncRNAs acting as scaffolds linking chromatin regulatory proteins. Chromatin remodeling includes altering chromatin structure by altering the extent of DNA supercoiling. Chromatin remodeling includes altering chromatin structure by genomic imprinting. Chromatin remodeling includes altering chromatin structure by altering the composition of histones within nucleosomes. Describe the importance of this process to transcription. Select the four correct answers. These alterations can be used to activate transcription of a gene by opening its enhancer sequences These alterations can be used to activate transcription of a gene by opening its promoter sequences. These alterations can be used to reExplanation / Answer
The two correct answers are:
Chromatin remodeling includes altering chromatin structure byaltering the positioning of nucleosomes with respect to specific DNA sequences.
Chromatin remodeling includes altering chromatin structure byaltering the composition of histones within nucleosomes.
Basically, chromatin remodeling is the dynamic modification of chromatin architecture which actually allows the regulatory transcription machinery proteins to access the DNA and hence control gene expression.
Such remodeling is principally carried out by:
covalent histone modifications by specific enzymes, i.e., histone acetyltransferases (HATs), deacetylases(HDACs), methyltransferases, and kinases.
ATP-dependent chromatin remodeling complexes which restructures the nucleosomes.
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