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Can you define and identify the significance of Okazaki fragments, DNA ligase, a

ID: 66845 • Letter: C

Question

Can you define and identify the significance of Okazaki fragments, DNA ligase, and primer RNA during DNA replication?

1. Okazaki fragments are short DNA fragments synthesized in a ____ manner.

2. Okazaki fragments appear on the ___ strand during DNA replication.

3. DNA ligase forms ___ bonds in gaps between DNA Okazaki fragments

4. These gaps are generated when ___ removes the RNA primers.

5. RNA primers are formed by ___ and serve as an initiation point for DNA synthesis on the template.

Words given for the blanks are : leading, lagging, peptide, phosphodiester, continuous, discontinuous, RNA primase, and DNA polymerase I.

Explanation / Answer

1. Okazaki fragments are short DNA fragments synthesized in a discontinuous manner.

2. Okazaki fragments appear on the lagging strand during DNA replication.

3. DNA ligase forms phosphodiester bonds in gaps between DNA Okazaki fragments

4. These gaps are generated when DNA polymerase I removes the RNA primers.

5. RNA primers are formed by _RNA primase__ and serve as an initiation point for DNA synthesis on the template.

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