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3. Height in humans is controlled by the additive action of genes and environmen

ID: 68755 • Letter: 3

Question

3. Height in humans is controlled by the additive action of genes and environmental factors. For the purposes of this problem, assume that height is controlled by four genes: A, B, C, and D, and that there are no environmental effects. Assume further that dominant additive alleles contribute two units of height, and recessive alleles contribute one unit of height. Given these assumptions, can two individuals of intermediate height have offspring that are much taller and much shorter than either parent? If so, how can this happen? Show genotypes of parents and offspring to confirm your answer.

Explanation / Answer

Height controlling gene : A, B, C and D

Tall genotypes : AA, BB, CC and DD

Short genotypes : aa, bb, cc and dd

intermediate height genotypes: Aa, Bb, Cc and Dd.

Cross between 2 intermediate height genotypes : Aa X Bb

male/ female

A

a

B

AB

aB

b

Ab

ab

AB: Tall offspring

aB and Ab : intermediate height offspring

ab: Short offspring.

Thus cross between parents of intermediate height produce one tall, two intermediate height offspring and one short offspring.

male/ female

A

a

B

AB

aB

b

Ab

ab

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