When this protein is placed in an electricfield, it does not migrate. When a mut

Question

When this protein is placed in an electricfield, it does not migrate. When a mutant form of this protein isplaced in an electric field, it migrates toward the anode (positiveelectrode). Which of the following amino acid substitution mighthave occurred? 1) A valine replaced aglutamine 2) A valine replaced alysine 3) A lysine replaced avaline 4) A glycine replaced atryptophan 5) A valine replaced anaspartate When this protein is placed in an electricfield, it does not migrate. When a mutant form of this protein isplaced in an electric field, it migrates toward the anode (positiveelectrode). Which of the following amino acid substitution mighthave occurred? When this protein is placed in an electricfield, it does not migrate. When a mutant form of this protein isplaced in an electric field, it migrates toward the anode (positiveelectrode). Which of the following amino acid substitution mighthave occurred? A valine replaced aglutamine A valine replaced alysine A lysine replaced avaline A glycine replaced atryptophan A valine replaced anaspartate 1) A valine replaced aglutamine 2) A valine replaced alysine 3) A lysine replaced avaline 4) A glycine replaced atryptophan 5) A valine replaced anaspartate

Explanation / Answer

2) valine is neutral. lysine is positive. Valine replaces the positive charge, so the protein is now overallnegative (due to the other residues), and can now migrate to theanode.

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