Many allergy medications contain antihistamines, compounds that contain amine gr

Question

Many allergy medications contain antihistamines, compounds that contain amine groups (RNH2, where R refers to an organic functional group).

Part B

One over-the-counter product lists the active ingredient as "diphenhydramine HCl." What does this designation mean?

1. The designation indicates that the amine has reacted with HCl to form an ammonium salt and is present in that form. Ammonium hydrochlorides are less soluble than amines. 2. The designation indicates that the amine doesn't react with HCl. 3. The designation indicates that the amine has reacted with HCl to form an ammonium salt and is present in that form. Ammonium hydrochlorides are more soluble than amines. 4. The designation indicates that the amine has reacted with HCl and H2O with CO2 have released.

Explanation / Answer

Answer is 3

Many drugs are high-molecular-weight amines that are weak bases. These amines are not soluble in water, this can be a problem since this means that they wont be soluble in body fluids, thats why they are offered in the form of a salt that is soluble and able to be administered by injection or oral medication.

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