Which of the following statements about genome-wide association studies (GWAS) i
ID: 69584 • Letter: W
Question
Which of the following statements about genome-wide association studies (GWAS) is false?
A. GWAS can be used even if more than one gene can cause the disease of interest. B. Studies using GWAS only examine SNPs that occur very rarely (<0.001%) in the population, as those SNPs are most likely to cause disease. C. GWAS use SNPs to compare populations of people with disease and people without disease to look for SNPs more likely to be present in those with disease. D. Sometimes GWAS will identify SNPs that are associated with a disease but these SNPs do not affect the gene product of the gene that causes the disease.Explanation / Answer
The correct answer is option (B)
(B) Studies using GWAS only examine SNPs that occur very rarely (<0.001%) in the population, as those SNPs are most likely to cause disease.
The GWAS is a tool for investigating the genetic basis for human disease. GWAS looks for SNP's that are present frequently in people who have certain kinds of diseases.The goal of the GWAS is to identify the risk factors genetically and know who is at the risk of that disease. Complementation factor H, a gene as a risk factor for age related degenration was identified by GWAS.
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