Which of these statements about vancomycin are true? [Select all that apply.] Re

Question

Which of these statements about vancomycin are true? [Select all that apply.] Resistance to vancomycin has not yet emerged in a clinical setting. vancomycin was widely used clinically following its discovery in the mid- 1950's. Vancomycin is produced by a soil microbe found in the jungles of Borneo. O Vancomycin is produced by Streptomyces orientalis. Vancomycin has significant ototoxic and nephrotoxic side effects when given in a pure form. Vancomycin is a glycopeptide. Intense marketing of vancomycin led to its widespread use. yet been documented. Vancomycin is produced by staphylococci.

Explanation / Answer

True statements for vancomycin (among the given options)

2. Vancomycin was widely used clinically following its discovery in the mid-1950s.

3. Vancomycin is produced be a soil microbe found in the jungles of Borneo.

5. Vancomycin has significant ototoxic and nephrotoxic side effects when given in the pure form.

6. Vancomycin is a glycopeptide antibiotic and it blocks the cell wall construction of microbes.

7. Intense marketing of vancomycin by El Lilly in 1958 led to its widespread use.

all the above are true for vancomycin. rest all the statements are wrong, as vancomycin is produced by  Amycolatopsis orientalis which is a soil bacteria, and not by Streptomyces orientalis. similarly, there are lots of resistance found for this antibiotic like Escherichia coli and Staphylococcus aureus. also vancomycin use is restricted in case of infection by staphylococcus aureus bacteria.

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