Which of the following is typically associated with an autosomal recessive patte

Question

Which of the following is typically associated with an autosomal recessive pattern of inheritance?

An affected offspring has one or more affected parents

An affected individual with one affected parent will have 50% of its offspring affected

Two affected heterozygous individuals will have 25% of their offspring unaffected

An affected offspring has two unaffected parents

An affected offspring has one or more affected parents

An affected individual with one affected parent will have 50% of its offspring affected

Two affected heterozygous individuals will have 25% of their offspring unaffected

An affected offspring has two unaffected parents

Explanation / Answer

d,.An affected offspring has two unaffected parents is typically associated with an autosomal recessive pattern of inheritance. This is the only true statement.

It is because if both the parents are unaffected, but carrier than there is 25% chance of an offspring to be affected. While rest will be unaffected.

AaXAa will give AA,Aa,Aa,aa

Out of which only aa will be affected in recessive autosomal disorder.

While rest of the options are incorrect because, option a is not mendatory, unaffected parents can also produce affected offspring as described above.

Option b is incorrect because as seen in cross the unaffected carrer parents produce 75%unaffected offspring.

Option C is false as there is 75% possibility of being unaffected in this case when Two affected heterozygous crossed.

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