5. Some of the metabolic pathways were just introduced at the end of CHEM 400/50
ID: 705052 • Letter: 5
Question
5. Some of the metabolic pathways were just introduced at the end of CHEM 400/500, summer 2018. Fill in missing the information for these pathways in the following table. We will be studying these pathways and the body’s regulation of these pathways during Biochemistry II. (18 pts)
Pathway
Overall Reaction (major reactants and products)(1 pt each)
Functions of the pathway. Include both major and minor functions (0.5 pt each).
Is the pathway aerobic or anaerobic? Is it considered catabolic, anabolic or both. Explain (1 pt each)
In what tissues does this take place and in what compartment(s) of the cell is this pathway localized? (0.5 pt each)
Glycolysis
{Type full overall reaction here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Gluconeogenesis
{Type full overall reaction here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Tricarboxylic Acid Cycle
{Type overall reaction of one round here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Fatty Acid Oxidation
{Type overall reaction of one round here starting with a C16 saturated fatty acid}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Electron Transport
{Type overall reaction here starting with NADH}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Oxidative Phosphorylation
{Type overall reaction of here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Pathway
Overall Reaction (major reactants and products)(1 pt each)
Functions of the pathway. Include both major and minor functions (0.5 pt each).
Is the pathway aerobic or anaerobic? Is it considered catabolic, anabolic or both. Explain (1 pt each)
In what tissues does this take place and in what compartment(s) of the cell is this pathway localized? (0.5 pt each)
Glycolysis
{Type full overall reaction here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Gluconeogenesis
{Type full overall reaction here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Tricarboxylic Acid Cycle
{Type overall reaction of one round here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Fatty Acid Oxidation
{Type overall reaction of one round here starting with a C16 saturated fatty acid}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Electron Transport
{Type overall reaction here starting with NADH}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Oxidative Phosphorylation
{Type overall reaction of here}
{Type full answer here}
{Type full answer here}
{Type full answer here}
Explanation / Answer
Please note: This is a multi-part question. As per the rule, we can answer only first four subquestions. So if you consider the first question of glycolysis that itself has 4 subquestions. Anyhow, answer to 1 and 2 nd questions are given below.
1. Glycolysis
a)Overall Reaction :
C6H12O6 + 2 NAD+ + 2 ADP + 2 P (phosphate) --------> 2 H3(C=O)COOH (pyruvic acid) + 2 ATP + 2 NADH + 2 H+
Major reactant: Glucose ; product s ATP (know as energy currency) + pyruvic acid
b) Functions of the pathway ;
c) Is the pathway aerobic or anaerobic? Is it considered catabolic, anabolic or both. Explain (1 pt each)
Glycolysis, is an anaerobic process. None of its steps involve the use of oxygen. However, immediately upon finishing glycolysis, the cell must continue respiration in either an aerobic or anaerobic direction; this choice is made based on the circumstances of the particular cell.
Since the glucose is broken down into pyruvic acid and energy. The process is catabolic. see the definition in the parenthesis (Catabolism involves all of the metabolic processes that tear down biomolecules, while anabolism is all of the metabolic processes that build biomolecules)
d) The process happens in the exa-mitochondrial portion of the cell.
2. Gluconeogenesis
a) Overall Reaction (major reactants and products)(1 pt each)
2 pyruvate + 4 ATP + 2 GTP + 2 NADH + 6 H2O ’ glucose + 4 ADP + 2 GDP + 6 Pi + 2 NAD+ + 2 H+
b)Functions of the pathway. Include both major and minor functions (0.5 pt each)
Gluconeogenesis converts the pyruvate to glucose which passes back into the bloodstream, restoring that used by the erythrocytes and brain cells.
c) Is the pathway aerobic or anaerobic? Is it considered catabolic, anabolic or both. Explain (1 pt each)
Since glucose is synthesised from lower molecules. This is anabolic reaction. Also. since the pathway does use oxygen , this is an anaerobic reaction,
.
d) Gluconeogenesis occurs in the liver (approximately 90 %) and in the kidney (about 10 %), only those two tissues can provide blood glucose by gluconeogenesis.
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.