What is the metabolic significance of the following observation? Liver tissue bu

Question

What is the metabolic significance of the following observation? Liver tissue but not muscle tissue contains an appreciable level of glucose-6-phosphatase.

A. Glucose-6-phosphatase plays an important role in liver and not muscle because a key liver function is to manufacture glucose for export. B. Glucose-6-phosphatase inhibits production of citric acid cycle intermediates in all cells so the liver removes excess amounts from the blood. C. Glucose-6-phosphatase controls the level of ATP production only in tissues that can carry out gluconeogenesis. D. Glucose-6-phosphatase is produced in liver cells and then small amounts of glucose-6-phosphatase are delivered to muscle cells.

Explanation / Answer

A. Glucose-6-phosphatase plays an important role in liver and not muscle because a key liver function is to manufacture glucose for export.

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