Acquired immunity involves both a humoral immune response and a cell-mediated im
ID: 7128 • Letter: A
Question
Acquired immunity involves both a humoral immune response and a cell-mediated immune response. Some components of the immune system are involved in only the humoral response, some are involved in only the cell-mediated response, and some are involved in both responses.Sort the following items depending on if they are involved in the humoral response, cell-mediated response, or both.
cytokines
plasma cells
B cells
antigen-presenting cells
helper T cells
cytotoxic T cells
memory cells
antibodies
clonal selection
Explanation / Answer
Cell-mediated immunity is an immune response that does not involve antibodies but rather involves the activation of macrophages and NK-cells, the production of antigen-specific cytotoxic T-lymphocytes , and the release of various cytokines in response to an antigen. Cellular immunity protects the body by:
1. activating antigen-specific cytotoxic T-lymphocytes that are able to destroy body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;
2. activating macrophages and NK cells, enabling them to destroy intracellular pathogens; and
3. stimulating cells to secrete a variety of cytokines that influence the function of other cells involved in adaptive immune responses and innate immune responses.
The humoral immune response protects against free-floating foreign molecules (antigens). Thedefense involves antibodies which are secreted by B cells. The B cells are activated when a specific antigen binds to the antibody,which is located on the surface of the B cells. This activation results in the production of memory B cells and plasma B cells thatare specific for that antigen. Plasma B cells release antibodies specific for the antigen. Memory B cells express the antibody ontheir surfaces and become important for the secondary immune response. The humoral immune response is also vital forvaccines.
According to this
Cytokines-These are usually there for Cell Mediated Response.
Plasma Cells-Humoral Response and these will produce antibodies.
B Cells- Humoral Response and these will produce antibodies.
Antigen Presenting Cells - Cell Mediated Immunity. these will present antigens on their surface to T cells
Helper T cells- Cell Mediated Immunity
Cytotoxic T cells- Cell Mediated Immunity an these will go and attack the calls infected with a virus etc
Memory Cells - Humoral Immunity- These are cells which will show a rapid proliferation of antibodies in case of reinection by the causative agent
Antibodies- Humoral Immunity- These are the main component of Humoral Response.
Clonal selection -Both Humoral and Cell Mediated
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