1.Most cancers result from: a.inherited cancer-causing mutant alleles b.mutation

ID: 71395 • Letter: 1

Question

1.Most cancers result from:

a.inherited cancer-causing mutant alleles

b.mutations caused by DNA polymerase

c.exposure to viruses and/or acquisition of random mutations over time

d.chance events during meiosis

e.mitotic nondisjunction

2.Infection with human papilloma virus (HPV) strain 16 or 18 can lead to cervical cancer. the reason for this is:

a.the replicating viruses express oncogenes that disrupt p53 and RB activity

b.They sometimes integrate their oncogenes that disrupt p53 and RB activity into host DNA

c.They insert at random and disrupt normal cellular genes

d.they insert their DNA in the p53 genes

e.these viruses often convert cellular protooncogenes into oncogenes

3.Cancerous tumors are most often derived from :

a. a single cell with a single mutation

b.a single cell with multiple mutations

c.multiple cells each with different, single mutations

d.multiple cells wioth multiple mutations

e.none of the above

4.Which of the following best describes an individual that is heterozygous for a recessive mutant tumor-suppressor gene?

a.they are certain to have cancer

b.they will almost certainly not develop cancer

c.they are at higher risk to develop cancer

d.they will pass on the cancer to their offspring

e.none of the above

1.Most cancers result from: Option C is correct

c.exposure to viruses and/or acquisition of random mutations over time

2.Infection with human papilloma virus (HPV) strain 16 or 18 can lead to cervical cancer. the reason for this is: Option A is coorect

a.the replicating viruses express oncogenes that disrupt p53 and RB activity

3.Cancerous tumors are most often derived from : Option D is correct

d.multiple cells with multiple mutations

4.Which of the following best describes an individual that is heterozygous for a recessive mutant tumor-suppressor gene? Option D is coorect

d.they will pass on the cancer to their offspring

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