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mating between two types of laboratory rats with normal phenotypes produces 68 o

ID: 72183 • Letter: M

Question


mating between two types of laboratory rats with normal phenotypes produces 68 offspring, 15 of which showed a hyperactive behavioral abnormality. The other 53 offspring were behaviorally normal. Assume that the parents were heterozygous. Using a chi square test, are these results expected from the mendelian inheritance perspective? Do these data fit the model that hyperactivity is caused by a recessive allele of a single gene? Be sure to show the number of observed, number of expected, degrees of freedom, and how to calculate the chi square statistic.

Explanation / Answer

Chi square is a a statistical method for assessing the goodness of fit between a set of observed values and the values expected theoretically.

Chi square= sum of (observed-expected)2

expected