19. A plant-derived protein known as colchicine can be used to poison cells by b

Question

19. A plant-derived protein known as colchicine can be used to poison cells by blocking the formation of the spindle. Which of the following would result if colchicine is added to a sample of cells in G2? A. The cells would immediately die. B. The cells would be unable to begin M and stay in G2. C. Each resultant daughter cell would also be unable to form a spindle D. The chromosomes would segregate but in a disorderly pattern E. The chromosomes would coil and shorten but not align. 20. Which of the following is TRUE concerning cancer cells? A. They do not exhibit density-dependent inhibition when growing in culture B. When they stop dividing, they do so at random points in the cell cycle C. They are not subject to cell cycle controls D. All of the above. E. Only B and C. 21. CAM plants keep stomata closed in daytime, thus reducing loss of water. They can do this because they A. use photosystem l and photosystem II at night B. fix CO2 into sugars in the bundle-sheath cells C. fix CO2 into pyruvate in the mesophyll cells D. perform the Calvin cycle during the night E. fix CO2 into organic acids during the night 22. Which of the following phases of the cell cycle is NOT part of interphase? D. G1 123. Which of the following does not occur during the Calvin cycle? A. release of oxygen B. oxidation of NADPH C. carbon fixatio D, regeneration of the CO2 acceptor E. consumption of ATP 124. As described in class, to clone the mutant agamous allele we used A. a primer with a unique transposon sequence B. a primer with a unique wild-type AGAMOUS sequence. C. a primer with a unique adapter overhang sequence. D. Both A and C. E. Both A and B 125. The function of the AGAMOUS gene is to regulate A. RNA translation B. gene transcription C. RNA splicing D, DNA replication. E. RNA degradation. 126. The flower phenotype of Arabidopsis plants homozygous for the loss-of-function agamous mutant allele is A conversion of stamens to petals B. conversion of carpels to sepals. C. conversion of sepals to petals. D. Both B and C E. Both A and B Page 17 of 22

Explanation / Answer

19). c. The chromosomes would coil and shorten but have no spindle to which to attach.

Colchicine is a plant derived alkaloid that prevent the formation of spindle fibres. So, the coiled chromosomes shorten but they cannot attach to the spindle because no spindle is formed in the presence of colchicine. Colchicine is used in the treatment of gout.

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