The population of Tasmanina Devils is rapidly disappearing because of a communic

Question

The population of Tasmanina Devils is rapidly disappearing because of a communicable oral-facial tumor that leaves the animals unable to eat or drink. Recent evidence shows that diseased animals all have [____] tumor cell karyotype, even though they may have [____] non-tumor cell karyotypes. The shared tumor cell karyotype demonstrated that there was no [____] causing the disease and that the tumor must be transmitted through exchange of [____]. Most Tasmanian Devils have (the) [____], meaning that little natural resistance to the tumor exists in a population and that the infecting cell is treated as (a) [____].

(1) a defective, the same, virus, chromosomes, same immune system, self-tissue

(2) a shared, normal, endogenous defect, tissue, unrelated MHC molecules, foreign-tissue

(3) an identical, typical, environmental source, defective chromosomes, disease, compatible

(4) a chromosome-deficient, normal, internal agent, a virus, tumor, incompatible

(5) the same, different, external agent, tumor cells, same MHc locus, compatible tissue match

Explanation / Answer

(5) the same, different, external agent, tumor cells, same MHc locus, compatible tissue match

The population of Tasmanina Devils is rapidly disappearing because of a communicable oral-facial tumor that leaves the animals unable to eat or drink. Recent evidence shows that diseased animals all have [_the same___] tumor cell karyotype, even though they may have [_different___] non-tumor cell karyotypes. The shared tumor cell karyotype demonstrated that there was no [__external agent__] causing the disease and that the tumor must be transmitted through exchange of [__tumour cells__]. Most Tasmanian Devils have (the) [same MHc locus____], meaning that little natural resistance to the tumor exists in a population and that the infecting cell is treated as (a) [_compatible tissue match___]

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