The ability of mutants 1, 2, 3, & 4 to grow on media containing growth supplemen

Question

The ability of mutants 1, 2, 3, & 4 to grow on media containing growth supplements A, B, C and D is summarized in the table below. In order to answer the multiple choice questions, determine the biosynthetic pathway and which mutants affect which step. The order of the biosynthetic pathway from start to finish is: Mutant #1 inactivates the enzyme that catalyzes the enzymatic reaction. Increased frequency of Down syndrome is associated with: Which of the following is FALSE about stem cells? Which of the following is FALSE about RNA gene silencing?

Explanation / Answer

66. DBAC. C is the final product of the pathway which has resulted in growth in all four mutants given. Presence of A did not produce B, where as in the presence of B A is produced and presence of D has produced BA and C, hence the order of the biosynthetic pathway is DBAC.

67. Answer option A last enzyme. The explanation is given above.

68. Answer option B, older maternal age. It is a condition where extra chromosome in full or partial of chromosome 21 is seen. Hence it is not inherited due to a mutant gene. It is related only with maternal age.

69. The option A is false regarding stem cells. The embryo need not be killed to take the stem cell.

70. All the above is the correct answer, RNA mediated gene silencing decreases translation, also results in degradation of double standard RNA, and formation of double standard RNA.

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