What are the major products of the reactions of1-phenylethanone(acetophenone) wi

Question

What are the major products of the reactions of1-phenylethanone(acetophenone) with each of the following a. Bromine in acetic acid b. Iodine in sodium hydroxide solution c. NaOH then (ii) add ethyl iodide d. Ethyl magnesium bromide followed by acidic work up e. NaOH and benzaldehyde f.NaOH and methanal I will appreciate it if i can get answers THANKS. What are the major products of the reactions of1-phenylethanone(acetophenone) with each of the following a. Bromine in acetic acid b. Iodine in sodium hydroxide solution c. NaOH then (ii) add ethyl iodide d. Ethyl magnesium bromide followed by acidic work up e. NaOH and benzaldehyde f.NaOH and methanal I will appreciate it if i can get answers THANKS.

Explanation / Answer

I think a. oxidation may take place 2. Iodoform reaction, sodium hydroxide will abstract a proton togive enolate and the enolate will react with iodine. 3. reaction with NaOH will give enolate and enolate will react as anucleophile with ethyl iodide. 4. grignard reaction will take place to give a tertiaryalcohol. 5. reaction with NaOH will give enolate and enolate will react withaldehyde to give an aldol product. 6. reaction with NaOH will give enolate and enolate will react withaldehyde to give an aldol product. hope this helps

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